I-57 exits in Missouri

Q: How many exits does I-57 have in Missouri?

I-57 has 5 numbered exits in Missouri, running an east–west from milepost 1 to milepost 12.

Q: What's the best exit to stop at on I-57 in Missouri?

Exit 12 (Charleston;Wyatt) is the strongest all-around stop, with 14 places to eat and 2 gas stations. See our full ranking of the best stops on I-57 in Missouri.

Every exit on I-57 through Missouri (an east–west run from milepost 1 to 12), with what's actually there — pulled from the same database that powers the Pit Stop app.

5exits

64places to eat

14gas stations

33hotels

14sights

🚗 Driving I-57 right now? Pit Stop shows every one of these exits live as you approach — gas, food, hotels & rest areas on iPhone & CarPlay, even offline. Get Pit Stop — $1.99 once →

Exit-by-exit guide

Exit	Destinations	Gas	Food	Hotels	Sights
Exit 1A	Memphis	Conoco, Conoco, Phillips 66 +1	Burger King, Casey's, Lambert's Cafe Ozark +15	Americas Best Value Inn & Suites, Days Inn & Suites by Wyndham Sikeston, Choice Hotels +7	Sikeston Depot Museum & Cultural Center, Heartland Monuments LLC
Exit 1B	Saint Louis	Conoco, Conoco, Phillips 66 +1	Casey's, Rally's, Lambert's Cafe Ozark +16	Days Inn & Suites by Wyndham Sikeston, Country Hearth Inns & Suites - Sikeston, Motel 6 Sikeston- Mo +9	Heartland Monuments LLC, Sikeston Depot Museum & Cultural Center
Exit 4	Bertrand	—	—	—	Playground
Exit 10	Charleston;East Prairie	MFA Oil, Exxon, Cenex +1	Pizza Hut, Hunt Brothers Pizza, SUBWAY +10	Quality Inn Charleston - Sikeston, Super 8 by Wyndham Charleston/Sikeston East MO, Eagle Inn +3	Warren E. Hearns Museum, The First Steps Into the Louisiana Purchase, Mississippi County Hist Soc +4
Exit 12	Charleston;WyattTravel centerOpen 24h	Cenex, Love's	El Cerrito - Charleston, Casey's, Huddle House +11	Super 8, Super 8 by Wyndham Charleston/Sikeston East MO, Quality Inn Charleston I-57 +2	Mississippi County Hist Soc, The First Steps Into the Louisiana Purchase

Quick answers

How many exits does I-57 have in Missouri?

I-57 has 5 numbered exits in Missouri, running an east–west from milepost 1 to milepost 12.

What's the best exit to stop at on I-57 in Missouri?

Exit 12 (Charleston;Wyatt) is the strongest all-around stop, with 14 places to eat and 2 gas stations. See the full ranking →

I-57 in other states

I-57 in Arkansas (41 exits)
I-57 in Illinois (87 exits)

← All interstates in Missouri

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