All 50 exits ranked by what a road-tripper actually needs: real food choice, easy gas, 24-hour service, and the stops worth a detour. Winners below.
Milepost 3 · 14 places to eat · 11 gas stations · 3 hotels · 24/7 travel center
Milepost 81 · 14 places to eat · 11 gas stations · 7 hotels · 24/7 travel center
Milepost 227 · 14 places to eat · 9 gas stations · 2 hotels · 24/7 travel center
Milepost 48 · 14 places to eat · 4 gas stations · 3 hotels · 24/7 travel center
Milepost 52 · 7 places to eat · 8 gas stations · 3 hotels · 24/7 travel center
Milepost 5 · 14 places to eat · 14 gas stations · 2 hotels
Milepost 26 · 14 places to eat · 10 gas stations · 10 hotels
Milepost 123 · 14 places to eat · 12 gas stations · 14 hotels
Milepost 184 · 14 places to eat · 14 gas stations · 14 hotels
Milepost 214 · 14 places to eat · 12 gas stations · 4 hotels
← Every US-66 exit in Missouri
Pit Stop shows gas, food, hotels & must-see stops at every exit ahead — $1.99 once, offline, on iPhone & CarPlay.