All 45 exits ranked by what a road-tripper actually needs: real food choice, easy gas, 24-hour service, and the stops worth a detour. Winners below.
Milepost 40 · 29 places to eat · 13 gas stations · 22 hotels · ♥ Old Courthouse, Gateway Arch
Milepost 34 · 29 places to eat · 15 gas stations · 14 hotels · open 24 hours · ♥ Bayer Insectarium, Saint Louis Zoo
Milepost 37 · 29 places to eat · 12 gas stations · 11 hotels · ♥ Shelley House, Pulitzer Arts Foundation
Milepost 34 · 29 places to eat · 10 gas stations · 11 hotels · ♥ Saint Louis Art Museum, Mildred Lane Kemper Art Museum
Milepost 36 · 29 places to eat · 10 gas stations · 12 hotels · ♥ Saint Louis Science Center, Saint Louis Science Center
Milepost 38 · 29 places to eat · 10 gas stations · 11 hotels · ♥ Scott Joplin House, The Griot Museum of Black History
Milepost 39 · 29 places to eat · 11 gas stations · 13 hotels · ♥ Campbell House Museum, City Museum
Milepost 36 · 29 places to eat · 11 gas stations · 10 hotels · ♥ Missouri Botanical Garden
Milepost 36 · 29 places to eat · 10 gas stations · 12 hotels · ♥ World Chess Hall of Fame
Milepost 37 · 29 places to eat · 12 gas stations · 13 hotels · ♥ International Photography Hall of Fame and Museum
Pit Stop shows gas, food, hotels & must-see stops at every exit ahead — free, offline, on iPhone & CarPlay.